This will work with other Steam VR games, and I did get it to work with SkyrimVR also.

• Summary: (Software you will need)
  • Virtual Desktop
  • SideQuest
  • SteamVR
  • Fallout 4 VR

• Details:
  • Virtual Desktop:
    • Purchase the version from your Oculus 2 Headset, there are several versions of Virtual Desktop, and you will need this one to avoid problems.
  • SideQuest
    • This is needed to be able to “side load” unofficial patches, so you will need to install the “Virtual Desktop” patch from SideQuest
    • You can download SideQuest here: https://sidequestvr.com/
    • More info about SideQuest here: https://uploadvr.com/sideloading-quest-how-to/
  • SteamVR
    • This app is available from the Steam store on your computer.
  • Fallout 4 VR
    • Purchase this from the SteamVR store.

• Running Fallout 4 VR:
  • Connect to Virtual Desktop from your Oculus Quest 2 headset
  • Click the menu button to show the VR Menu
  • Launch SteamVR
  • Run Fallout 4 VR

At this point, if you are not using mods for Fallout 4 VR, then you’re done and can play.

If you are using mods that require the Script Extender, you cannot just “Run Fallout 4 VR” because it will not run the script extender. For me, I had to do the following:

• Running Fallout 4 VR with Mods:
  • Connect to Virtual Desktop from your Oculus Quest 2 headset
  • Click the menu button to show the VR Menu
  • Launch SteamVR
  • Click the menu button
  • Show Desktop
  • In Vortex, click the FO4SE
  • Click the menu button
  • Return to VR

This setup is just a summary of what worked for me based on the following article:
https://uploadvr.com/how-to-play-pc-vr-oculus-quest-2/

Vortex is the mod manager used by NexusMods:
https://www.nexusmods.com/fallout4/?